Table 1.
Details of the eligible studies in this meta-analysis.
| First author | Yr | Province | Exp. | Ctr. | Total number | cExp. | cCtr. | Male | Female | Smoke | Alcohol | Diabetes | Hypertension | Age | BMI | MoCA | Country | 16S region | Seq. Tech. |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Yinting Huang | 2021 | Guangdong | PSCI | nPSCI | 56 | 29 | 27 | 34 | 22 | NA | NA | 31.03 | 58.62 | 62.76 | NA | 5.38 | China | V3–V4 | MiSeq Benchtop Sequencer |
| Yongqiang Liu | 2020 | Shanghai | PSCI | nPSCI | 65 | 30 | 35 | 49 | 16 | NA | NA | NA | NA | 64.90 | 23.41 | 17.46 | China | V3–V4 | Illumina MiSeq PE250 |
| Huidi Wang | 2022 | Guangdong | PSCI | nPSCI | 83 | 34 | 49 | 68 | 15 | 44.10 | 32.40 | 35.30 | 70.60 | 61.50 | 23.70 | NA | China | V4 | Illumina iSeq 100 |
| Feng Rongjian | 2021 | Sichuan | PSCI | HC | 47 | 24 | 23 | 26 | 21 | 54.17 | 45.83 | NA | NA | 63.17 | 24.73 | 13.25 | China | Whole 16S region | PacBio Sequel |
| Li Yamei | 2022 | Sichuan | PSCI | nPSCI(HC) | 36 | 12 | 12 (12) | 20 | 16 | NA | NA | NA | NA | 60.75 | 25.20 | 19.92 | China | Whole 16S region | PacBio Sequel |
| Li Yonghua | 2022 | Shandong | PSCI | nPSCI(HC) | 67 | 29 | 18 (20) | 34 | 33 | 27.60 | 17.20 | 37.90 | 44.80 | 68.50 | NA | 13.30 | China | V3–V4 | MiSeq |
| Liu Zhirong | 2021 | Sichuan | PSCI | HC | 47 | 24 | 23 | 26 | 21 | 50.00 | 45.80 | NA | NA | 63.01 | 25.34 | 13.25 | China | Whole 16S region | PacBio Sequel |
| Song Xinna | 2021 | Guangdong | PSCI | nPSCI | 141 | 120 | 21 | NA | NA | NA | NA | NA | NA | NA | NA | NA | China | NA | MiSeq |
| Yi Ling | 2020a | Zhejiang | PSCI | nPSCI | 93 | 53 | 40 | 62 | 31 | 17.00 | 41.50 | 24.50 | 77.40 | 72.20 | 24.70 | 13.70 | China | V3–V4 | MiSeq Benchtop Sequencer |
| Yi Ling | 2020b | Zhejiang | PSCCID | nPSCCID | 66 | 41 | 25 | 31 | 35 | 51.20 | NA | 29.30 | 58.50 | 69.63 | 25.14 | 13.17 | China | V3–V4 | MiSeq Benchtop Sequencer |
| Feng Dan | 2022 | Sichuan | PSCI | HC | 39 | 20 | 19 | 22 | 17 | NA | NA | NA | NA | 61.25 | 24.96 | 12.15 | China | Whole 16S region | PacBio |
| Du Jun | 2022 | Jiangsu | VCIND | HC | 60 | 40 | 20 | 29 | 31 | 35.00 | 42.50 | NA | NA | 61.73 | NA | 22.08 | China | V3–V4 | NA |
BMI = body mass index, cCtr = cases in control group, Ctr = control group, Exp = experimental group, HC = healthy control, MoCA = montreal cognitive assessment, NA = not available, nExp = cases in experiment group, nPSCI = non-PSCI, PSCI = post-stroke cognitive impairment, Seq. Tech = sequencing technique.