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. 2023 Sep 1;102(35):e34764. doi: 10.1097/MD.0000000000034764

Table 2.

Meta-analysis of diversity of gut microbiota of patients with PSCI.

Terns Number of studies Participants I2 P Effect [95%CI] z P
ACE 7 294 85.8 <.001 0.10 [−0.55, 0.74] 0.293 .770
 HC 4 167 84.9 <.001 −0.39 [−1.22, 0.43] −0.934 .350
 nPSCI 3 127 79.5 <.001 0.75 [−0.11, 1.60] 1.718 .08
Chao 1 8 464 77.9 <.001 −0.31 [−0.77, 0.15] −1.307 .191
 HC 4 178 25.3 .260 −0.57 [−0.93, −0.21] −3.128 .002
 nPSCI 4 286 88.3 <.001 0.04 [−0.84, 0.92] 0.091 .927
Shannon 10 485 76.9 <.001 0.08 [−0.31, 0.47] 0.412 .680
 HC 5 258 68.1 .014 −0.12 [−0.60, 0.37] −0.469 .639
 nPSCI 5 227 83.9 <.001 0.29 [−0.35, 0.94] 0.888 .375
Simpion 9 530 0 .626 −0.21 [−0.40, −0.02] −2.117 .034
 HC 4 178 0 .542 −0.31 [−0.62, −0.01] −2.030 .042
 nPSCI 5 352 0 .520 −0.12 [−0.38, 0.11] −1.082 .279

HC = healthy control, nPSCI = non-PSCI, PSCI = post-stroke cognitive impairment.