Table 2.

Results for discovery phase and validation phase for 8 validated microRNAs (bold = positively validated)

miRNA	Discovery				Validation
	UC-NM vs UC-Dys, Student P	UC-NM vs UC-Dys, AUROC	UC-CRC sequence, ANOVA P	UC-CRC vs Sp-CRC, Student P	UC-NM vs UC-Dys, Student P	UC-NM vs UC-Dys, AUROC	UC-CRC sequence, ANOVA P	UC-CRC vs Sp-CRC, Student P
let-7f	0.003	0.720	0.012	5.20E-04	0.707	0.554	0.006	0.384
miR-20b	2.92E-04	0.820	1.58E-06	0.005	0.016	0.734	3.10E-06	0.110
miR-24	1.60E-06	0.900	2.22E-08	0.045	0.199	0.620	0.140	7.26E-04
miR-29a	3.90E-07	0.920	2.21E-09	0.062	0.645	0.517	0.003	0.021
miR-31	0.002	0.760	4.87E-06	0.020	2.64E-04	0.774	1.90E-06	0.015
miR-106a	6.16E-06	0.900	1.69E-06	0.001	0.002	0.777	0.003	0.012
miR-135b	4.57E-09	0.960	1.65E-13	0.010	5.12E-08	0.923	4.40E-05	0.040
miR-195	8.42E-04	0.800	4.33E-07	0.611	1.45E-04	0.831	1.40E-04	2.44E-04

AUROC, area under the receiver operating curve; Sp-CRC, sporadic colorectal cancer; UC-CRC, ulcerative colitis–associated colorectal cancer; UC-Dys, ulcerative colitis–associated dysplasia; UC-NM, ulcerative colitis–associated normal mucosa.