Table 3.
Univariate Analysis and Multivariate Logistic Analysis for All Participants
| Univariate Analysis | Multivariate Analysis | ||||
|---|---|---|---|---|---|
| n (%) | OR (95% CI) | Crude P | OR (95% CI) | Adjusted P | |
| Age | |||||
| ≤35 | 3950 (84.26%) | 1.0 | |||
| >35 | 738 (15.74%) | 0.43 (0.36, 0.52) | <0.001 | 0.51(0.42, 0.61) | <0.001 |
| Education | |||||
| ≤6 years | 141 (3.01%) | 1.0 | |||
| 6–9 years | 1485 (31.68%) | 1.05 (0.74, 1.49) | 0.786 | ||
| 9~12 years | 902 (19.24%) | 0.93 (0.65, 1.33) | 0.682 | ||
| >12 year | 2160 (46.08%) | 1.09 (0.77, 1.54) | 0.635 | ||
| Infertility years | |||||
| ≤5 year | 3830 (81.7%) | 1.0 | |||
| 5~10 years | 750 (16%) | 1.07 (0.92, 1.26) | 0.380 | ||
| >10 year | 108 (2.3%) | 0.79 (0.53, 1.17) | 0.245 | ||
| FSH | |||||
| ≤10 | 3968 (84.64%) | 1.0 | |||
| >10 | 720 (15.36%) | 0.79 (0.67, 0.93) | 0.004 | 0.98(0.83, 1.17) | 0.845 |
| E2 | |||||
| ≤55 | 3411 (72.76%) | 1.0 | |||
| >55 | 1277 (27.24%) | 0.84 (0.74, 0.96) | 0.010 | 0.86(0.76, 0.99) | 0.031 |
| P | |||||
| ≤1 | 3761 (80.23%) | 1.0 | |||
| >1 | 927 (19.77%) | 0.97 (0.84, 1.12) | 0.664 | ||
| PRL | |||||
| ≤10 | 1452 (30.97%) | 1.0 | |||
| >10 | 3236 (69.03%) | 1.01 (0.89, 1.14) | 0.918 | ||
| LH | |||||
| ≤5 | 2822 (60.2%) | 1.0 | |||
| >5 | 1866 (39.8%) | 1.03 (0.92, 1.16) | 0.624 | ||
| T | |||||
| ≤0.45 | 2530 (53.97%) | 1.0 | |||
| >0.45 | 2158 (46.03%) | 1.23 (1.10, 1.38) | 0.001 | 1.13(1.00, 1.28) | 0.042 |
| AMH | |||||
| ≤3 | 2740 (58.45%) | 1.0 | |||
| >3 | 1948 (41.55%) | 1.47 (1.31, 1.66) | <0.001 | 1.15(1.01, 1.32) | 0.036 |
| Reason of infertility | |||||
| Primary | 2360 (50.34%) | 1.0 | |||
| Secondary | 2328 (49.66%) | 0.86 (0.76, 0.96) | 0.010 | 0.99(0.88, 1.12) | 0.857 |
| Treatment regimen | |||||
| Natural cycles or short cycle | 16 (0.34%) | 1.0 | |||
| Antagonist protocol | 1188 (25.34%) | 1.65 (0.53, 5.14) | 0.3903 | ||
| GnRH agonist protocol | 2075 (44.26%) | 2.40 (0.77, 7.48) | 0.1299 | ||
| Depot GnRHa protocol | 1409 (30.06%) | 2.64 (0.85, 8.21) | 0.0946 | ||
| Oocyte retrieval season | |||||
| Non-summer time | 2573 (55.14%) | 1.0 | |||
| Summer time (May-August) | 2093 (44.86%) | 1.10 (0.98, 1.23) | 0.120 | ||
| Holiday season | |||||
| Non-CNY Holiday Season (Mar. ~ Dec.) | 4449 (94.9%) | 1.0 | |||
| CNY Holiday Season (Jan ~ Feb) | 239 (5.1%) | 0.62 (0.47, 0.82) | 0.001 | 0.62(0.47, 0.82) | 0.001 |
| Number of oocytes retrieval | |||||
| 0–5 | 932 (19.91%) | 1.0 | |||
| 6–10 | 1654 (35.33%) | 1.62 (1.37, 1.92) | <0.001 | 1.44 (1.20, 1.71) | <0.001 |
| 11–15 | 1364 (29.14%) | 2.09 (1.76, 2.49) | <0.001 | 1.71 (1.41, 2.07) | <0.001 |
| 16 and more | 731 (15.62%) | 2.06 (1.68, 2.51) | <0.001 | 1.59 (1.27, 1.99) | <0.001 |
Abbreviations: AMH, anti-Müllerian hormone; E2, estrogen; FSH, Follicle-Stimulating Hormone; LH, luteinizing hormone; P, progesterone; PRL, prolactin; T, testosterone; CNY, Chinese New Year.