TABLE 2.

LncRNAs as potential biomarkers of Gastric Cancer.

LncRNA	Expression	Potential biomarker	AUC	Sample type	Clinical implication	References
CCAT1	Up	Diagnosis and prognosis	0.89	Tissue and serum	Poor survival outcomes	Xiao et al. (2021)
TCLlnc1	Up	Diagnosis and prognosis	0.97	Tissue and plasma	Tumor distant metastasis and poor survival outcomes	Hu et al. (2022)
DRAIR	Down	Diagnosis and prognosis	0.89	Tissue and plasma	Poor survival outcomes	Jin (2021)
NR038975	Up	Diagnosis	0.71	Tissue and plasma	Advanced TNM stage	Wei et al. (2021)
lncRNA-GC1	Up	Diagnosis	0.90	Tissue and serum	Advanced TNM stage	Guo et al. (2020)
	Up	Prognosis and predictive	0.70	Plasma	Poor survival outcomes and worse response to chemotherapy	Song et al. (2022)
LINC00152/CYTOR	Up	Prognosis	—	Serum	Advanced TNM stage and poor survival outcomes	Ou et al. (2021)
PTCS3	Down	Diagnosis and prognosis	0.92	Plasma	Poor survival outcomes	Zhang et al. (2020)
LINC00355	Up	Prognosis	—	Tissue and plasma	Advanced TNM stage, distant metastasis, and poor survival outcomes	Zhao et al., 2023, Zhao et al., 2020
lnc-SLC2A12-10:1	Up	Diagnosis	0.77	Tissue and plasma	Advanced TNM stage	Zheng et al. (2020)
LINC01614	Up	Prognosis	—	Tissue	Poor survival outcomes	Chen et al. (2021)
LINC00941	Up	Prognosis	—	Tissue	Poor survival outcomes	Liu et al. (2019)
CEBPA-AS1	Up	Diagnosis and prognosis	0.82	Tissue and plasma	Tumor size, Bormann type, and TNM stage	Piao et al. (2020)
H19	Up	Diagnosis	0.85	Serum	Advanced TNM Stage	Zhou et al. (2020)
HOXA11-AS	Up	Diagnosis and prognosis	0.92	Tissue and serum	Poor survival outcomes and TNM stage	Liu et al. (2019)
B3ALT5-AS1	Up	Diagnosis and prognosis	0.81	Serum	Poor survival outcomes, LNM and TNM stage	Feng et al. (2020)
SSTR5-AS1	Up	Prognosis	—	Tissue	Poor survival outcomes and distant metastasis	Cheng et al. (2020)
MIAT	Up	Diagnosis	0.89	Serum	Poor survival outcomes and TNM stage	Xu et al. (2020)
DIRC1	Up	Diagnosis and prognosis	0.77	Tissue	Poor survival outcomes	Lin et al. (2022)
HCP5	Up	Diagnosis	0.82	Serum	Differentiation, lymph node metastasis, and nerve invasion	Qin et al. (2021)
p4516	Up	Prognosis	—	Tissue	Poor differentiation, advanced TNM stage and poor survival outcomes	Nie et al. (2019)
PANDAR, FOXD2-AS1, and SMARCC2	Up	Diagnosis	0.84	Plasma	Poor differentiation and advanced TNM	Yang et al. (2019)
FAM49B-AS, GUSBP11, and CTDHUT	Up	Diagnosis	0.82	Plasma	—	Zheng et al. (2019)