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. 2023 Aug 2;78(9):2148–2161. doi: 10.1093/jac/dkad196

Table 2.

Published protein binding percentages for the NAPPA penicillins

Penicillin % Protein binding reported
Amoxicillin28 18
Benzylpenicillin29 60
Flucloxacillin30 95
Piperacillin31 30