Table 3.

MIC cut-offs used for plots (mg/L)

Antibiotic	MIC S cut-off	MIC R cut-off
Amoxicillin	2	8
Benzylpenicillin	0.25	2
Flucloxacillin	—	2
Piperacillin	8	16

These cut-off values are based on EUCAST PKPD (non-species-related) breakpoints, apart from flucloxacillin where the cut-off of 2 mg/L for MSSA is used (inferred from the MSSA MIC for oxacillin, since EUCAST and CLSI do not publish MSSA MICs or clinical breakpoints for flucloxacillin).^32,33