Table 2.
Comparison of plasma sclerostin within all Aβ− and Aβ+ participants and subgroups stratified by APOE ε4 status and sex, respectively.
| Aβ− | Aβ+ | P | P* | |
|---|---|---|---|---|
| SOST in all participants | 56.51 ± 22.14 | 71.49 ± 25.00 | 0.003 | 0.008 |
| SOST in APOE ε4 non-carriers | 55.94 ± 22.63 | 80.93 ± 27.18 | <0.001 | 0.001 |
| SOST in APOE ε4 carriers | 63.42 ± 15.06 | 60.42 ± 16.98 | 0.728 | 0.368 |
| SOST in males | 69.55 ± 28.18 | 87.07 ± 24.28 | 0.078 | 0.050 |
| SOST in females | 51.12 ± 16.68 | 62.28 ± 20.87 | 0.020 | 0.033 |
Student’s t test or Chi-square tests were employed as appropriate. Data are presented in mean ± SD in pmol/L, and P values in bold font were considered as significant (P < 0.05). P* represents P values adjusted for age, sex and APOE ε4 status.