Table 3.

Correlations between plasma sclerostin levels and AD biomarkers among all participants and subgroups stratified by brain Aβ status.

	All participants		Aβ−		Aβ+
	ρ	P	ρ	P	ρ	P
NFL	0.337	<0.001	0.445	<0.001	0.095	0.587
GFAP	0.314	0.001	0.218	0.081	0.067	0.703
t-tau	−0.017	0.865	−0.018	0.889	−0.267	0.121
p-tau181	0.393	<0.001	0.279	0.025	0.143	0.434
p-tau231	0.316	0.002	0.241	0.053	0.114	0.541
Aβ42	0.097	0.348	0.217	0.090	0.061	0.737
Aβ40	0.283	0.005	0.336	0.007	0.153	0.395
Aβ42/40	−0.155	0.133	−0.076	0.559	−0.128	0.479

Unadjusted correlation coefficients (ρ) and P values between plasma sclerostin and AD-related biomarkers were calculated using Spearman’s correlation analysis.

P values in bold font were considered as significant (P < 0.05).