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. 2023 Sep 4;13:14529. doi: 10.1038/s41598-023-41684-3

Table 2.

ICU outcomes, physical function, and symptom burden at ICU discharge (Analysis 1).

Factor Overall (n = 64) Short IMV (n = 34; 53%) Prolonged IMV (n = 30; 47%) P value
Time to first mobilize (days) 9 [7–13] 7 [5–8] 12 [11–20] < 0.001
ICU LOS (days) 11 [8–18] 8 [6–10] 19 [13–31] < 0.001
ICU Mobility Scale at ICU discharge 3 [1–4] 3 [1–5] 3 [1–3] 0.170
Physical function at ICU discharge
MRC sum score (points) 56 [46–60] 60 [58–60] 51 [32–55] < 0.001
 < 48 points 18 (28.1) 4 (11.8) 14 (46.7) 0.002
Handgrip strength (kg) 15.2 [8.4–22.5] 18.0 [11.3–24.5] 10.6 [6.1–16.5] 0.003
Male < 11 kg, female < 7 kg 18 (28.1) 5 (14.7) 13 (43.3) 0.011
Male < 28 kg, female < 18 kg 54 (88.5) 26 (78.8) 28 (100.0) 0.013
Grip and release test score (/10 s) 17 [10–23] 17 [10–23] 16 [8–22] 0.481
Foot tapping test score (/10 s) 14 [9–20] 15 [11–18] 12 [0–21] 0.181
ESAS sum score at ICU discharge (points) 19 [8–33] 19 [5–32] 19 [9–33] 0.415
Post-ICU LOS (days) 4 [1–7] 4 [2–6] 4 [0–7] 0.532
Readmitted to ICU (%) 5 (7.8) 1 (2.9) 4 (13.3) 0.177
Discharged home (%) 15 (23.4) 11 (32.4) 26 (13.3) 0.085
Barthel Index at hospital discharge 15 [0–75] 25 [5–85] 5 [0–45] 0.040

ESAS edmonton symptom assessment system, ICU intensive care unit, LOS length of stay, MRC medical research council, IMV invasive mechanical ventilation.

Values are expressed as n (%) or median [interquartile range].