Table 2.
LAP<4% | LAP≥4% | p | |
---|---|---|---|
n | 253 | 111 | |
Age (years) | 55.00 [44.00, 61.00] | 59.00 [52.00, 64.50] | <0.001 |
Race/ethnicity (n, %) | 0.003 | ||
NHA | 7 (3.1) | 7 (6.9) | |
NHB | 63 (27.8) | 13 (12.9) | |
Hispanic | 147 (64.8) | 70 (69.3) | |
NHW | 10 (4.4) | 11 (10.9) | |
Male sex (n, %) | 81 (32.0) | 52 (46.8) | 0.01 |
BMI (kg/m2) | 29.71 [26.22, 33.08] | 29.95 [26.42, 32.69] | 0.97 |
Diabetes mellitus (n, %) | 30 (12.3) | 27 (25.0) | 0.005 |
Hypertension (n, %) | 91 (37.4) | 75 (69.4) | <0.001 |
Hyperlipidemia (n, %) | 76 (31.3) | 63 (58.3) | <0.001 |
Smoking (n, %) | 0.023 | ||
Never | 184 (73.6) | 66 (59.5) | |
Past | 30 (12.0) | 18 (16.2) | |
Present | 36 (14.4) | 27 (24.3) | |
CAC (AU) | 0.00 [0.00, 0.00] | 40.00 [11.00, 83.00] | <0.001 |
CAD-RADS (value) | 0.00 [0.00, 1.00] | 2.00 [1.00, 2.00] | <0.001 |
Total Cholesterol (mg/dL) | 181.00 [160.00, 214.00] | 188.50 [157.25, 222.75] | 0.362 |
LDL-C (mg/dL) | 104.00 [81.00, 128.50] | 109.00 [86.00, 140.00] | 0.278 |
HDL-C (mg/dL) | 50.00 [41.00, 59.00] | 48.00 [41.25, 59.00] | 0.306 |
Creatinine (mg/dL) | 0.80 [0.71, 0.94] | 0.81 [0.74, 0.97] | 0.26 |
HbA1c (%) | 5.60 [5.30, 5.95] | 5.75 [5.38, 6.35] | 0.082 |
Lipoprotein(a) (nmol/L) | 65.00 [19.00, 156.00] | 60.00 [18.00, 130.00] | 0.736 |
Statin use at baseline (%) | 82 (32.9) | 46 (44.2) | 0.059 |
SBP (mmHg) | 123.77 [115.04, 133.66] | 124.78 [117.25, 134.61] | 0.338 |
DBP (mmHg) | 75.35 [70.87, 80.91] | 75.22 [70.18, 80.22] | 0.686 |
NCP burden (%) | 0.00 [0.00, 0.00] | 43.77 [37.11, 50.88] | <0.001 |
CP burden (%) | 0.00 [0.00, 0.00] | 1.61 [0.49, 3.65] | <0.001 |
Total plaque burden (%) | 0.00 [0.00, 0.00] | 46.95 [39.14, 53.91] | <0.001 |
Total CP vol (mm3) | 0.00 [0.00, 0.00] | 10.84 [3.68, 32.01] | <0.001 |
Total NCP vol (mm3) | 0.00 [0.00, 0.00] | 366.26 [212.77, 627.19] | <0.001 |
Total LAP vol (mm3) | 0.00 [0.00, 0.00] | 69.55 [35.30, 112.69] | <0.001 |
Total plaque vol (mm3) | 0.00 [0.00, 0.00] | 378.88 [228.18, 656.93] | <0.001 |
EAT (mL) | 79.00 [58.50, 108.50] | 105.00 [80.50, 135.50] | <0.001 |
10-year ASCVD risk (%) | 3.81 [1.40, 9.15] | 8.12 [4.00, 14.07] | <0.001 |
BMI: Body mass index, CAC: coronary artery calcium, LDL-C: low-density lipoprotein cholesterol, HLD-C: high-density lipoprotein cholesterol, HbA1c: hemoglobin A1c, SBP: average systolic blood pressure, DBP: average diastolic blood pressure, NCP: non-calcified plaque, NHA= non-Hispanic Asian, NHB= non-Hispanic Black, NHW=non-Hispanic White, CP: calcified plaque, LAP: low-attenuation plaque, EAT: epicardial adipose tissue, ASCVD: atherosclerotic cardiovascular disease risk by pooled cohort equations.