Table 2. All-cause, cardiovascular and non-cardiovascular mortality in relation to cigarette smoking.
Never smoking |
Former smoking | Current smoking | P-value† | P-value‡ | ||||||
All | Remote | Recent | All | Light-to- moderate |
Heavy | |||||
In multiple Cox regression, the adjusted variables included age, body mass index, pulse rate, alcohol intake, serum total cholesterol and triglycerides, fasting plasma glucose and the prevalence of hypertension and diabetes mellitus at baseline. †Refers to P-value for trend from never to former and to current smoking. ‡Refers to P-value for trend from never smoking to remote and recent former smoking, and to light-to-moderate and heavy current smoking. | ||||||||||
Number of participants | 311 | 334 | 201 | 133 | 923 | 783 | 140 | |||
Number of person-years | 2127 | 2297 | 1410 | 886 | 6568 | 5586 | 982 | |||
All-cause mortality | ||||||||||
Number of deaths | 53 | 77 | 42 | 35 | 137 | 115 | 22 | |||
Rate per 1000 person-years | 24.9 | 33.5 | 29.8 | 39.5 | 20.9 | 20.6 | 22.4 | |||
Age-adjusted HR (95% CI) | 1 | 1.29 (0.91–1.83) | 1.09 (0.72–1.63) | 1.69 (1.10–2.59) | 1.24 (0.90–1.72) | 1.17 (0.84–1.63) | 2.25 (1.33–3.80) | 0.25 | 0.06 | |
Multivariate-adjusted HR (95% CI) | 1 | 1.20 (0.84–1.72) | 0.99 (0.65–1.50) | 1.62 (1.04–2.52) | 1.19 (0.85–1.68) | 1.11 (0.79–1.58) | 2.30 (1.34–4.07) | 0.36 | 0.08 | |
Cardiovascular mortality | ||||||||||
Number of deaths | 30 | 28 | 15 | 13 | 48 | 45 | 3 | |||
Rate per 1000 person-years | 14.1 | 12.2 | 10.6 | 14.7 | 7.3 | 8.1 | 3.1 | |||
Age-adjusted HR (95% CI) | 1 | 0.87 (0.52–1.45) | 0.70 (0.38–1.30) | 1.19 (0.62–2.30) | 0.87 (0.55–1.39) | 0.89 (0.55–1.42) | 0.71 (0.21–2.42) | 0.60 | 0.78 | |
Multivariate-adjusted HR (95% CI) | 1 | 0.72 (0.42–1.23) | 0.57 (0.30–1.09) | 1.04 (0.52–2.10) | 0.78 (0.48–1.29) | 0.79 (0.48–1.31) | 0.68 (0.19–2.44) | 0.38 | 0.59 | |
Non-cardiovascular mortality | ||||||||||
Number of deaths | 23 | 49 | 27 | 22 | 89 | 70 | 19 | |||
Rate per 1000 person-years | 10.8 | 21.3 | 19.1 | 24.8 | 13.6 | 12.5 | 19.3 | |||
Age-adjusted HR (95% CI) | 1 | 1.85 (1.13–3.04) | 1.59 (0.91–2.77) | 2.35 (1.31–4.21) | 1.71 (1.07–2.72) | 1.54 (0.96–2.48) | 3.72 (1.96–7.06) | 0.06 | 0.01 | |
Multivariate-adjusted HR (95% CI) | 1 | 1.90 (1.12–3.07) | 1.54 (0.87–2.73) | 2.40 (1.32–4.37) | 1.71 (1.05–2.78) | 1.52 (0.93–2.51) | 3.98 (2.03–7.83) | 0.06 | 0.01 |