Table 2. Pain outcomes of participants in the DANPAIN-Biobank.
| Variables | Pain-free (n=70) | High impact chronic pain (n=201) | Osteoarthritis pain (n=81) | P |
|---|---|---|---|---|
| Pain duration, years, median (25th–75th percentiles) | 0 | 12.0 (6.5–21.8) | 2.0 (1.0–4.0) | <0.001 |
| Peak pain intensity last week, NRS 0–10, mean (SD) | 0 | 7.2 (1.8) | 6.8 (2.1) | 0.10 |
| Average pain intensity last week, NRS 0–10, mean (SD) | 0 | 5.7 (1.9) | 5.5 (2.2) | 0.56 |
| Least pain intensity last week, NRS 0–10, mean (SD) | 0 | 3.9 (2.1) | 3.6 (2.6) | 0.30 |
| Pain intensity at physical activity last week, NRS 0–10 mean (SD) | 0 | 6.3 (2.3) | 6.4 (2.2) | 0.77 |
| Widespread pain index, pain sites, 0–19, mean (SD) | 0 | 11.5 (5.1) | 2.0 (1.3) | <0.001 |
| Pain diagnoses, n (%) | ||||
| Wide spread pain | 0 | 143 (71%) | 0 | |
| Back pain | 0 | 24 (12%) | 0 | |
| Osteoarthritic pain | 0 | 0 | 81 (100%) | |
| Other | 0 | 34 (17%) | 0 | |
| Pain disability (PDI 5 items: 0–50, higher is worse), mean (SD) | 0 | 37.1 (11.6) | 26.1 (13.6) | <0.001 |
| PDI family/home responsibilities, 0–10 mean (SD) | 0 | 6.4 (2.2) | 4.8 (2.9) | <0.001 |
| PDI recreation 0–10, mean (SD) | 0 | 7.3 (2.2) | 6.9 (2.8) | 0.2 |
| PDI social activity 0–10, mean (SD) | 0 | 6.3 (2.5) | 4.1 (2.9) | <0.001 |
| PDI occupation 0–10, mean (SD) | 0 | 7.1 (2.5) | 4.4 (3.4) | <0.001 |
| PDI sexual behavior 0–10, mean (SD) | 0 | 5.9 (3.0) | 3.8 (3.4) | <0.001 |
| Analgesic treatment, n (%) | ||||
| No analgesic treatment | 70 (100%) | 22 (11%) | 12 (15%) | |
| Paracetamol | 0 | 130 (65%) | 62 (77%) | |
| NSAID | 0 | 52 (26%) | 21 (26%) | |
| Opioid | 0 | 67 (33%) | 10 (12%) | |
| Antidepressants†, pain indication | 0 | 63 (31%) | 1 (1%) | |
| Antiepileptics, pain indication | 0 | 38 (19%) | 2 (2%) | |
| Cannabinoids | 0 | 11 (5%) | 0 | |
| Low dose naltrexone | 0 | 11 (4%) | 1 (1%) | |
| Local treatments‡ | 0 | 7 (3%) | 0 |
†, tricyclic antidepressants, duloxetine, venlafaxine; ‡, transcutaneous electric nerve stimulation =2, Qutenza =1, Versatis =1, Botox =1, peripheral nerve field stimulation =1, spinal cord stimulation =1. P values represents differences between the two pain groups. DANPAIN, the Danish Pain Research Biobank; SD, standard deviation; NRS, Numerical Rating Scale; PDI, Pain Disability Index; NSAID, non-steroidal anti-inflammatory drugs.