Table 2. Human evidence of NO regulation of aqueous humor dynamics.
| Authors | Key findings |
|---|---|
| Nathanson et al. (32) | eNOS decreased in trabecular meshwork, Schlemm’s canal and ciliary body in primary open angle glaucoma patients |
| Doganay et al. (33)/Galassi et al. (34) | NO decreased in aqueous humor of primary open angle glaucoma patients |
| Kang et al. (35)/Magalhães da Silva et al. (36) | eNOS gene variation was associated with primary open angle glaucoma in women |
| Chuman et al. (37) | Intravenous injection of L-arginine reduced intraocular pressure in an average of 2 mmHg |
| Chang et al. (38) | Aqueous humor NO level was higher in the glaucoma patients than in the cataract patients |
NO, nitric oxide; eNOS, endothelial nitric oxide synthase.