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. 2023 Jun 6;11(10):352. doi: 10.21037/atm-22-5634

Table 2. Human evidence of NO regulation of aqueous humor dynamics.

Authors Key findings
Nathanson et al. (32) eNOS decreased in trabecular meshwork, Schlemm’s canal and ciliary body in primary open angle glaucoma patients
Doganay et al. (33)/Galassi et al. (34) NO decreased in aqueous humor of primary open angle glaucoma patients
Kang et al. (35)/Magalhães da Silva et al. (36) eNOS gene variation was associated with primary open angle glaucoma in women
Chuman et al. (37) Intravenous injection of L-arginine reduced intraocular pressure in an average of 2 mmHg
Chang et al. (38) Aqueous humor NO level was higher in the glaucoma patients than in the cataract patients

NO, nitric oxide; eNOS, endothelial nitric oxide synthase.