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. 2023 Aug 26;21:4134–4148. doi: 10.1016/j.csbj.2023.08.023

Fig. 4.

Fig. 4

Genomic instability of LEDGF/p75 is associated with patient prognosis. (A) Putative copy-number alterations of LEDGF/p75. (B) Mutations in LEDGF/p75. (C) Schematic diagram of LEDGF/p75 mutation sites. (D) The tumor mutation burden (TMB) of LEDGF/p75 across cancers. (E) Microsatellite instability (MSI) of LEDGF/p75 across cancers. (F) The heatmap shows correlations between LEDGF/p75 expression and 5 MMR genes in pancancer. (G-K) K—M plots show that alterations in LEDGF/p75 are associated with the overall survival of patients. * P < 0.05, * * P < 0.01, * ** P < 0.001.