Fig. 5.

LEDGF/p75 alternative splicing correlates with patient prognosis. (A) Read-in, read-out, and percent spliced in (PSI) values of LEDGF/p75 in pancancer and normal tissues. The red and gray labels represent cancers and adjacent normal tissues, respectively; black labels represent normal tissues. The parts labeled with "Reads-In" and "Reads-Out" on the Y-axis represent read count values, indicating exon splicing in or splicing out, respectively. (B-C) PSI differences between tumor and adjacent normal tissues and between tumor and GTEx normal tissues. The red line refers to 0.05, the dot size represents the tumor PSI value, and different cancers are marked in different colors. (D-K) The PSI value of LEDGF/p75 correlates with patient prognosis in several kinds of cancer.