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. 2023 Aug 26;21:4134–4148. doi: 10.1016/j.csbj.2023.08.023

Fig. 7.

Fig. 7

LEDGF/p75 significantly promotes the proliferation and metastatic ability of kidney cancer cells. (A) Expression of LEDGF/p75 and H3K36me3 in kidney cancer cell lines. (B-C) qRT—PCR and western blot experiments show the high efficiency of LEDGF/p75 knockdown. (D-F) CCK-8 and colony formation assays show that knockdown of LEDGF/p75 significantly inhibits proliferation of kidney cancer cells. (G) Transwell experiments show that knockdown of LEDGF/p75 significantly inhibits metastasis of kidney cancer cells.