Table 1.

Studies Evaluating the Effect of Non-surgical Periodontal Therapy on the Cardiovascular and/or Endothelial Function System in Individuals with Periodontitis: Duration, Population, and Periodontal Measures (relevant studies identified by literature review)

	Study Duration	Study Population	Periodontal Definition
Mercanoglu et al., 2004	6 wks	28; systemically healthy	CAL, PPD, GI, PI
Seinost et al., 2005	3 mos	30; systemically healthy	CAL, PPD, GI, PI
Blum et al., 2007	3 mos	13; systemically healthy	CAL, PPD, BOP
Elter et al., 2006	1 mo	22; systemically healthy	CAL, PPD
Li et al., 2011	3 mos	25; systemically healthy	CAL and PPD (interproximal), BOP, PI
Tonetti et al., 2007	6 mos	59; systemically healthy	PPD
Higashi et al., 2008	6 mos	32; systemically healthy	Self-reported questionnaire
Higashi et al., 2008	6 mos	26; individuals with hypertension	Self-reported questionnaire
Higashi et al., 2009	6 mos	48; individuals with CVD	Self-reported questionnaire
Piconi et al., 2009	12 mos	35; systemically healthy	PSR

CVD, cardiovascular disease; CAL, clinical attachment level; PPD, probing pocket depth; GI, gingival index; PI, plaque index; BOP, bleeding upon probing; PSR, Periodontal Screening and Recording.