Volcano plot depicting taxa with differential IgA coating between subjects receiving or not receiving specific medication. Horizontal axis indicates the fold change in ICI score (negative: enriched in healthy; positive: enriched in IBD). The vertical axis reflects −log10 p value of the test. Size of the circles indicate mean relative abundance, significant taxa (p < 0.05) colored in red.
(A) Biologics (untreated N = 173; treated N = 6).
(B) Immune modulators (untreated N = 169; treated N = 10).
(C) Antibiotics (N = 154, N = 26).
(D) Steroids (untreated N = 105; treated N = 74).