Table 5.

Unadjusted and adjusted logistic regression estimates between sleep and clinically significant depression and generalized anxiety symptoms at follow-up visit 15 (2015–2016) in the Study of Women’s Health Across the Nation

	CES-D ≥ 16		GAD ≥ 5
	N = 1197a		N = 1191b
	OR(95%CI)	p-value	OR(95%CI)	p-value
Unadjusted
Sleep regularity	1.73(1.14, 2.59)	.008	1.53(1.08, 2.17)	.016
Sleep midpoint
Between 2:00–4:00 AM	reference		reference
Outside 2:00–4:00 AM	2.04(1.42, 2.93)	<.001	1.18(0.88, 1.58)	.259
Adjusted
Sleep regularity	1.68(1.01, 2.79)	.046	1.62(1.07, 2.43)	.020
Sleep midpoint
Between 2:00–4:00 AM	reference		reference
Outside 2:00–4:00 AM	1.72(1.15, 2.57)	.008	1.05(0.76, 1.44)	.757

Note. CI, confidence interval, CES-D, Center for Epidemiological Studies Depression scale, GAD, Generalized Anxiety Disorder-7 scale, OR, odds ratio.

^aAdjusted N = 1160.

^bAdjusted N = 1156.

^cAdjusted for race and ethnicity, age, difficulty paying for basics, and employment, antidepressant use, anxiolytic use, total sleep time, wake after sleep onset, proportion of nights used sleep medication, proportion of nights with hot flashes/night sweats, and number of medical comorbidities.