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. Author manuscript; available in PMC: 2023 Sep 5.
Published in final edited form as: J Control Release. 2022 Aug 3;349:796–811. doi: 10.1016/j.jconrel.2022.07.040

Figure 7: Effect of CD44TA-LIP treatment on various T cell populations of mice during tuberculosis infection.

Figure 7:

Frequencies of resident memory CD4 and CD8 T cells (CD103+CD69+) in spleens (A) of untreated, and CD44TA-LIP treated mice. Percentages of IFN-γ and IL-2 expressing CD4 (B) and CD8 (C) T cells in spleens of untreated, and CD44TA-LIP treated mice. Frequencies of effector memory (D) and central memory (E) CD4 and CD8 T cells in spleens of untreated, and CD44TA-LIP treated mice. Treatment with CD44TA-LIP prior to infection is depicted as CD44TA-LIP (PT) whereas treatment with CD44TA-LIP after infection is depicted as CD44TA-LIP (CT) in all panels. CD44+CD62LloCCR7lo= Effector memory population; CD44+CD62LhiCCR7hi= Central memory population. *p < 0.05, **p < 0.001, ***p < 0.0001, ***p < 0.0001; t-test.