Table 2.

International Classification of Retinoblastoma and Prediction of outcomes of surgery

Groups	Criterion	Number of Patients in group based on the study [49] n = 249	Treatment and success rate
Group A	Retinoblastoma tumor with size <  = 3 mm.	23 (9%)	Chemo reduction with vincristine, etoposide and carboplatin for 6 cycles (CRD) plus thermotherapy or cryotherapy. 100%
Group B	RB tumor with size > 3 mm, has a location close to the macula or presents with small amount of subretinal fluid.	96 (39%)	CRD plus thermotherapy or cryotherapy. 93%
Group C	Eyes with localised seeding of the tumor.	21 (8%)	CRD plus thermotherapy or cryotherapy. 90%
Group D	Diffuse seeding of the tumor within the eyes.	109 (44%)	CRD plus thermotherapy or cryotherapy. 47%
Group E	Huge mass of the tumor covering a great proportion of the eye.	0 as the patients needed management with enucleation and hence were excluded from the study.	Enucleation with CRD in certain cases.