Table 3.
PPT values across structural and inflammatory severity for painful (n=285) and non-painful (n=285) finger joints separately.
| PPT mean kg/cm2 (SD) | Adjusted beta (95% CI) | Additional adjustment of KL grade/GS synovitis1, beta (95% CI) | |
|---|---|---|---|
| Painful finger joints | |||
| KL | |||
| Grade 0 (n=63) | 4.5 (1.9) | Ref. | Ref. |
| Grade 1 (n=41) | 4.3 (1.8) | −0.3 (−1.1, 0.4) | −0.3 (−1.0, 0.4) |
| Grade 2 (n=62) | 4.6 (2.2) | 0.0 (−0.7, 0.7) | 0.0 (−0.7, 0.7) |
| Grade 3 (n=55) | 3.2 (1.6) | −1.4 (−2.1, −0.7) | −1.2 (−1.9, −0.5) |
| Grade 4 (n=64) | 2.8 (1.2) | −1.9 (−2.5, −1.2) | −1.6 (−0.4, −0.9) |
| Continuous scales (grade 0–4) | −0.5 (−0.6, −0.3) | −0.4 (−0.6, −0.2) | |
| Erosive disease | |||
| No (n=231) | 4.1 (2.0) | Ref. | Ref. |
| Yes (n=54) | 2.8 (1.2) | −1.3 (−1.9, −0.7) | −1.0 (−0.6, −0.2) |
| GS synovitis | |||
| Grade 0 (n=159) | 4.3 (2.0) | Ref. | Ref. |
| Grade 1 (n=57) | 3.8 (2.0) | −0.5 (−1.1, 0.1) | 0.0 (−0.5, 0.6) |
| Grade 2 (n=43) | 3.3 (1.2) | −1.0 (−1.6, −0.3) | −0.3 (−0.9, 0.4) |
| Grade 3 (n=26) | 2.5 (1.5) | −1.8 (−2.6, −1.0) | −1.1 (−1.9, −0.3) |
| Continuous scales (grade 0–3) | −0.6 (−0.8, −0.3) | −0.3 (−0.5, −0.0) | |
| PD activity grade 1–3 | |||
| No (n=201) | 4.2 (2.0) | Ref. | Ref. |
| Yes (n=84) | 3.0 (1.3) | −1.3 (−1.8, −0.8) | −0.8 (−1.3, −0.3) |
| Non-painful finger joints | |||
| KL | |||
| Grade 0 (n=124) | 5.1 (2.3) | Ref. | Ref. |
| Grade 1 (n=52) | 5.0 (2.1) | −0.1 (−0.7, 0.6) | −0.0 (−0.7, 0.6) |
| Grade 2 (n=75) | 4.8 (2.0) | −0.3 (−0.9, 0.4) | −1.2 (−0.8, 0.4) |
| Grade 3 (n=24) | 4.2 (1.6) | −1.0 (−1.9, −0.1) | −0.9 (−1.9, 0.0) |
| Grade 4 (n=10) | 3.6 (1.3) | −1.4 (−2.7, −0.0) | −1.3 (−2.8, 0.1) |
| Continuous scales (grade 0–4) | −0.3 (−0.5, −0.1) | −0.2 (−0.5, −0.0) | |
| Erosive OA | |||
| No (n=271) | 5.0 (2.1) | Ref. | Ref. |
| Yes (n=9) | 3.6 (1.4) | −1.2 (−2.6, 0.2) | −1.1 (−2.5, 0.3) |
| GS synovitis | |||
| Grade 0 (n=264) | 5.0 (2.1) | Ref. | Ref. |
| Grade 1 (n=15) | 4.3 (1.4) | −0.7 (−1.8, 0.4) | −0.1 (−1.3, 1.1) |
| Grade 2 (n=5) | 3.4 (1.2) | −1.4 (−3.3, 0.4) | −1.3 (−3.2, 0.6) |
| Grade 3 (n=1) | 3.7 (NA) | −1.1 (−5.2, 2.9) | −1.1 (−5.2, 3.0) |
| Continuous scales (grade 0–3) | −0.6 (−1.3, −0.0) | −0.4 (−1.1, 0.2) | |
| PD activity grade 1–3 | |||
| No (n=271) | 5.0 (2.1) | Ref. | Ref. |
| Yes (n=14) | 3.9 (1.4) | −1.0 (−2.1, 0.2) | −0.5 (−1.7, 0.7) |
Linear regression. All analyses are adjusted for age, sex and BMI.
1
Analyses of KL and erosive OA are adjusted for GS synovitis grade while analyses of GS synovitis and PD activity are adjusted for KL grade. SD; standard deviation. CI; confidence interval. KL; Kellgren-Lawrence grade. GS; grey scale. NA; not applicable. PD; power Doppler.