TABLE 3.
Absorbed Dose to Red Marrow Estimated Using Image-Based Activity Concentrations in T9–L5 Vertebrae, Hip Bones, and Thoracic Aorta
Patient no. | Bone metastases | Vertebrae | Hip bones | Blood-based (skeletal average) | ||||
---|---|---|---|---|---|---|---|---|
Specific | Nonspecific | Total | Specific | Nonspecific | Total | |||
1 | No | 0.068 | 0.026 | 0.093 | 0.066 | 0.019 | 0.085 | 0.015 |
2 | No | 0.025 | 0.019 | 0.044 | 0.016 | 0.014 | 0.030 | 0.011 |
3 | Yes | 0.016 | 0.018 | 0.033 | 0.028 | 0.013 | 0.042 | 0.012 |
4 | No | 0.022 | 0.014 | 0.036 | 0.014 | 0.011 | 0.025 | 0.010 |
5* | Yes | 0.496 | 0.028 | 0.524 | 0.251 | 0.022 | 0.273 | 0.019 |
6 | No | 0.018 | 0.016 | 0.034 | 0.022 | 0.012 | 0.034 | 0.011 |
7 | No | 0.020 | 0.023 | 0.042 | 0.012 | 0.017 | 0.028 | 0.017 |
8 | No | 0.029 | 0.021 | 0.050 | 0.039 | 0.015 | 0.054 | 0.012 |
9 | No | 0.038 | 0.024 | 0.062 | 0.028 | 0.017 | 0.045 | 0.013 |
10 | No | 0.047 | 0.023 | 0.070 | 0.024 | 0.017 | 0.040 | 0.013 |
11 | Yes | 0.065 | 0.041 | 0.106 | 0.049 | 0.030 | 0.079 | 0.023 |
12 | Yes | 0.052 | 0.025 | 0.077 | 0.040 | 0.018 | 0.058 | 0.014 |
13 | No | 0.052 | 0.041 | 0.093 | 0.030 | 0.030 | 0.059 | 0.023 |
14 | Yes | 0.056 | 0.037 | 0.093 | 0.069 | 0.027 | 0.096 | 0.021 |
15 | Yes | 0.114 | 0.042 | 0.157 | 0.084 | 0.032 | 0.116 | 0.029 |
16 | Yes | 0.026 | 0.013 | 0.039 | 0.020 | 0.010 | 0.030 | 0.009 |
17 | No | 0.043 | 0.043 | 0.086 | 0.052 | 0.033 | 0.085 | 0.029 |
Removed from all averages because of large number of bone metastases.
Data are Gy/GBq. For vertebrae and hip bones, absorbed dose contributions were divided into specific (somatostatin receptor type 2–based) and nonspecific (blood-based, Eq. 4). Equation 5 was used for solely blood-based dosimetry in right column.