FIG. 3.

Clinical course for patients with mixed infections. Patient 10916 had multiorgan failure in the setting of difficult-to-control graft-versus-host disease. Infection with neither C. albicans nor A. fumigatus was suspected, and no antifungal therapy had been initiated prior to death. Patient 10149 had pulmonary infection with P. carinii followed by infection with A. fumigatus. Patient 7872 died of fusariosis. Patient 9937 died of disseminated yeast and mold infection after struggling for months with severe chronic graft-versus-host disease. (A to D) ▪, positive PCR result for blood; □, negative PCR result for blood; and ○, culture-negative blood specimen. (A) ×, lung sample culture positive for Aspergillus at autopsy; •, blood specimen culture positive for Torulopsis (Candida) glabrata. (B) ▿, normal chest radiograph; ▾, chest radiograph with infiltrates; ×, lung specimen culture positive for Aspergillus at autopsy; ∗, bronchoalveolar lavage fluid positive for P. carinii by silver stain. (C) +, sputum specimen culture positive for Fusarium; ×, skin biopsy specimen positive for hyphae; •, blood specimen culture positive for Fusarium. (D) +, blood specimen culture positive for a bacterial organism; ∗, cultures of organ specimens obtained at autopsy grew Torulopsis and sterile mycelia; ▴, blood culture grew a zygomycete; ▾, blood culture grew Prototheca; ⧫, blood culture grew Penicillium.