Figure 5.
Size tuning in DBA/2J and C57BL/6J mice.
(A) Example size tuning of a neuron showing obvious surround suppression (solid line) or no surround suppression (dotted line). (B) A much smaller proportion of suppressive cells were observed in DBA/2J mice (64.6% of neurons were suppressive in C57BL/6J mice, and 45.7% of neurons were suppressive in DBA/2J mice). (C) Larger classical receptive field (CRF) size and weaker surround suppression were observed in DBA/2J mice (CRF: n = 51; suppressive index: n = 51) compared with C57BL/6J mice (CRF: n = 32, Mann-Whitney U test, *P < 0.05; suppressive index: n = 32, Mann-Whitney U test, *P = 0.0288). (D) A lower maximum response and no significant difference in spontaneous activity were observed in DBA/2J mice (maximum response (max): n = 70; spontaneous activity (spon): n = 79) compared with C57BL/6J mice (maximum response: n = 79; spontaneous activity: n = 70; Mann-Whitney U test, *P = 0.0147). Data are expressed as the mean ± SD. All experiments were repeated three times.