Table 2.

Clinical Outcomes Comparing Differences between Those Subjects Treated with Calfactant and Those Who Received Placebo

Clinical Outcomes	Effect Comparison (95% CI)*	P
Mortality (PICU discharge): HR†	1.78 (.53–6.05)	.35
First intervention (outcome = OI)‡
Treatment × time interaction	—	.64
Second intervention (outcome = OI)‡
Treatment × time interaction	—	.52
Deterioration in POPC score: OR†	.57 (.11–2.85)	.49
Deterioration in PCPC score: OR†	.45 (.09–2.22)	.33
Retreated (received the second intervention): OR†	.44 (.08–2.35)	.34
Expected no. of VFDs: RR†	1.11 (.88–1.41)	.37
Unsuccessful extubation§: OR†	.58 (.12–2.77)	.50

HR indicates hazard ratio; OR, odds ratio; RR, rate ratio.

^*All effects compare the calfactant group with the placebo group.

^†Adjusted for risk strata + PRISM score.

^‡Adjusted for risk strata.

^§Defined as free from mechanical ventilation for greater than 48 hours.