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. 2023 Sep 5;14:5408. doi: 10.1038/s41467-023-41119-7

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a Percentage of live HepG2 cells after 48-hour treatment with each NMT inhibitor (shown in black) compared with that of controls treated with diluent. Data are presented as mean values ± SD. The staurosporine-positive control is shown in red. b–d Percentage change in P. falciparum blood-stage development as measured by parasite DNA level fluorescence assay after 72-hour treatment with NMT inhibitors from each of the three prioritized compound families. Data are normalized to untreated controls set at 100%. Source data are provided as a Source Data file.