Table 2.

Novel genetic loci associated with lipid traits in individuals of African ancestry from multi-trait genome-wide association study

CHR	SNP	BP	A1	A2	EAF	BETA	SE	P-value	N	Genes	Traits
1	rs368884688	181315526	G	A	0.994	−0.267	0.046	7.20 x 10−09	13114	CACNA1E	HDL
1	rs368884688	181315526	G	A	0.994	−0.277	0.050	3.47 x 10−08	13115	CACNA1E	TG
3	rs149700703	45204966	T	G	0.008	0.232	0.040	5.68 x 10−09	31019	RPS24P8	TC
4	rs911749026	6362109	A	G	0.991	−0.229	0.041	1.64 x 10−08	13115	PPP2R2C	TG
7	rs13438114	31039982	A	G	0.189	0.025	0.005	4.85 × 10−08	123032	GHRHR	TC
8	rs77237080	91701696	G	A	0.064	−0.028	0.005	3.59 x 10−09	120770	TMEM64	HDL
8	rs74979471	91724679	A	G	0.070	−0.031	0.005	4.75 × 10−10	119930	TMEM64	TG
8	rs112773301	133214483	G	A	0.986	0.134	0.024	4.65 x 10−08	23589	KCNQ3	TG
9	rs6477710	99585314	G	T	0.069	−0.032	0.005	1.36 × 10−10	102013	ZNF782	HDL
9	rs113951466	103289530	T	C	0.077	−0.027	0.004	6.01 × 10−10	120770	MSANTD3-TMEFF1:TMEFF1	HDL
9	rs7850215	98327711	A	G	0.104	−0.023	0.004	2.06 × 10−09	120771	RP11-332M4.1	HDL
9	rs6477710	99585314	G	T	0.070	−0.047	0.008	5.65 x 10−10	104276	ZNF782	TC
9	rs4743855	94581258	T	C	0.107	−0.024	0.004	2.08 x 10−09	110284	ROR2	HDL
9	rs10819792	98834653	T	C	0.219	−0.016	0.003	6.03 × 10−09	120771	RP11-569G13.2	HDL
9	rs7041800	95951769	A	G	0.072	−0.043	0.007	4.72 x 10−09	104276	WNK2	TC
9	rs10819792	98834653	T	C	0.220	−0.024	0.004	1.36 x 10−08	123033	RP11-569G13.2	TC
9	rs113951466	103289530	T	C	0.077	−0.027	0.005	9.84 x 10−09	119930	MSANTD3-TMEFF1:TMEFF1	TG
9	rs7850215	98327711	A	G	0.105	−0.033	0.006	1.68 x 10-08	123032	RP11-332M4.1	TC
12	rs374366861	87353564	T	C	0.943	0.070	0.012	1.87 x 10−08	23589	RP11-324H9.1	TG

CHR chromosome, SNP single nucleotide polymorphism, BP base position, A1 effect allele, A2 other allele, EAF effect allele frequency, SE standard error, N sample size.

P-values are two-tailed calculated using MTAG and not adjusted for multiple comparisons.