Table 2.

Affinity between six target proteins and COS

Gene name	Protein name	Affinity(kcal/mol)
AKT1	RAC-alpha serine/threonine-protein kinase	− 8.3
HRAS	GTPase HRas	− 8.1
IGFR1	Insulin-like growth factor 1 receptor	− 7.4
HSP90AA1	Heat shock protein HSP 90-alpha	− 6.8
EGFR	Epidermal growth factor receptor	− 6.2
PTK2	Protein-tyrosine kinase 2	− 4.9