Figure 5.

Molecular docking results between two compounds (i.e., AT9283, dorsomorphin) and TEK

(A and B) docked pose for AT9283; (B) docked pose for dorsomorphin. TEK is displayed in gray color. AT9283 is represented by sticks and colored in cyan, and dorsomorphin is represented by sticks and colored in yellow. The residues of the pocket that interact with these two compounds are colored in magentas and red in (A) and (B), respectively. Hydrogen bonds are represented by the blue dashed lines. Hydrophobic interactions are represented by the gray dashed lines. Water bridges are represented by the orange dashed lines. Salt bridge is represented by the yellow dashed line.