Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Sep 5;13:14622. doi: 10.1038/s41598-023-41632-1

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

(a) Heatmap showing the expression levels of the DA proteins across control and patient samples. (b) Analysis of the secretome showing the protein–protein network of the 48 differentially abundant proteins in COL6-RD derived fibroblasts versus healthy fibroblasts. (c) Comparative meta analysis of the most overrepresented functional categories amongst the DA proteins in EVs versus those in the secretome (Metaescape). (d) Results of the MMP3 ELISA showing an increased concentration in serum from COL6-RD serum (mean values and SEM).