Table 1.
Rare variants uniquely significant in either meta-analysis or pooled analysis
| Analysis Type | RS Id | AF | Ancestry | Gene-Mutation |
|---|---|---|---|---|
| Meta-analysis | rs72646508 | 0.002 | AFR | PCSK9 p.Leu253Phe |
| Meta-analysis | rs145777339 | 0.003 | AMR | APOB p.Tyr3098= |
| Pooled | rs981175281 | 0.0002171081 | AFR | PDZRN3 intron_variant |
| Pooled | rs150401820 | 0.0007244627 | AFR | LRP4 p.Asp91Asp |
| Pooled | rs370601772 | 0.0004823927 | AFR | MYO19 p.Lys118Asn |
| Pooled | rs121908030 | 0.0001933862 | AFR | LDLR p.Asp389Asn |
| Pooled | rs28942084 | 7.236588e-05 | AFR | LDLR p.Pro770Leu |
| Pooled | rs142412517 | 0.001 | AMR | APOE p.Arg239Trp |