Fig. 5.

Clinical responses in patients with HCC administered CT017 CAR-GPC3 T cells. (a) Swimming plot of PFS (mITT analysis set); (b) Spider plot of tumor size change from baseline; Notes: Arrow marks the start time of combination therapy; (c) Relationship between Best overall response and change of AFP to baseline. Abbreviations: ADA, anti-drug antibodies; AFP, alpha-fetoprotein; CAR T, chimeric antigen receptor T cells; mITT, modified intention-to-treat analysis; PD, progressive disease; PR, partial response; SD, stable disease.