Table 3.
Accuracy of hypertension diagnosis at different blood pressure cut offs using daytime 24 h-ABPM as reference.
| BP cut off | Sensitivity (95% CI) | Specificity (95% CI) | PPV (95% CI) | NPV (95% CI) | LR (+) (95% CI) | LR (−) (95% CI) | AUROC (95% CI) |
|---|---|---|---|---|---|---|---|
| Standard BP measurement | |||||||
| ≥140/90 | 85 (78–91) | 57 (48–66) | 69 (61–76) | 78 (68–86) | 2.0 (1.6–2.5) | 0.3 (0.2–0.4) | 0.71 (0.66–0.77) |
| ≥135/85 | 89 (83–94) | 49 (40–58) | 66 (59–73) | 80 (70–89) | 1.8 (1.5–2.1) | 0.2 (0.1–0.4) | 0.69 (0.64–0.74) |
| ≥130/80 | 93 (88–97) | 38 (29–47) | 62 (55–69) | 84 (72–92) | 1.5 (1.3–1.7) | 0.2 (0.1–0.3) | 0.66 (0.61–0.70) |
| 1st uABP | |||||||
| ≥140/90 | 74 (66–81) | 75 (66–82) | 77 (68–84) | 72 (64–80) | 3.0 (2.1–4.1) | 0.4 (0.3–0.5) | 0.74 (0.69–0.80) |
| ≥135/85 | 85 (78–90) | 63 (54–71) | 72 (64–78) | 79 (69–86) | 2.3 (1.8–2.9) | 0.2 (0.2–0.4) | 0.74 (0.69–0.79) |
| ≥130/80 | 93 (87–96) | 52 (43–61) | 68 (61–75) | 87 (77–93) | 1.9 (1.6–2.3) | 0.1 (0.1–0.3) | 0.72 (0.67–0.77) |
| 2nd uABP | |||||||
| ≥140/90 | 64 (56–72) | 90 (84–95) | 88 (80–94) | 70 (62–77) | 6.6 (3.8–11.5) | 0.4 (0.3–0.5) | 0.77 (0.72–0.82) |
| ≥135/85 | 77 (69–84) | 70 (61–78) | 74 (66–81) | 74 (65–81) | 2.6 (2.0–3.5) | 0.3 (0.2–0.5) | 0.74 (0.68–0.79) |
| ≥130/80 | 91 (84–95) | 53 (44–62) | 68 (61–75) | 84 (74–91) | 1.9 (1.6–2.4) | 0.2 (0.1–0.3) | 0.72 (0.67–0.77) |
BP: blood pressure; uABP: unattended blood pressure; 24 h-ABPM: 24 h ambulatory blood pressure monitor; CI: confidence interval; PPV: positive predictive value; NPV: negative predictive value; LR: likelihood ratio.