Table 2.
Results of early embryo development in different groups.
| Index | Young group | Aged group | Aged + MT group | P1-value | P2-value | P3-value |
|---|---|---|---|---|---|---|
| Retrieved oocytes (n) | 51 | 55 | 54 | – | – | – |
| Maturation rate | 76.47(39/51) | 43.64(24/55) | 75.93(41/54) | 0.0006* | 0.9478 | 0.0006* |
| Fertility rate (%) | 74.36(29/39) | 75(18/24) | 75.61(31/41) | 0.9547 | 0.8972 | 0.9561 |
| Cleavage rate (%) | 93.1(27/29) | 83.33(15/18) | 96.77(30/31) | 0.5691 | 0.9527 | 0.2647 |
| High-quality embryo rate (%) | 37.04(10/27) | 33.33(5/15) | 50(15/30) | 0.8103 | 0.3247 | 0.2888 |
| Blastocyst formation rate (%) | 51.85(14/27) | 13.33(2/15) | 53.33(16/30) | 0.033* | 0.9109 | 0.0098* |
| High-quality blastocyst rate (%) | 25.93(7/27) | 0(0/15) | 20(6/30) | 0.0382* | 0.5944 | 0.1629 |
P1: Young group & Aged group P2: Young group & Aged + MT group P3: Aged group & Aged + MT group. High-quality embryo: 7–9 blastomeres at equal size on day 3, with no fragmentation or less than 15%. High-quality blastocyst: embryos that were ≥3BB on day 5 or ≥4BB on day 6 by the blastocyst grading system according to Gardner's criteria. Enumeration data were reported as percentages and compared by the χ2 test; *:P < 0.05, difference was statistically significant.