Table 4.

Identification of prototype components from NLXT in rats by UPLC-Q-TOF-MS.^E.

No	tR (min)	Identification	Experimental mass (m/z)	Error (ppm)	Adducts	Formula	MSE fragment ions (m/z)	Source
1	5.52	3-Hydroxybenzoic acid/ 4-Hydroxybenzoic acid	137.0236	−6.1	[M − H]-	C7H6O3	/	B
2	6.33	Parishin B/Parishin C	727.2093	0.3	[M − H]-	C32H40O19	/	C
3	7.86	HSYAa/iso	611.1608	0.3	[M − H]-	C27H32O16	504.1103[M-H- C7H5O]-	D
4	9.47	3-Hydroxybenzoic acid/ 4-Hydroxybenzoic acid	137.0236	−5.7	[M − H]-	C7H6O3	93.0341 [M-H-COO]-	D
5	10.12	Phenylacetaldehyde	119.0493	−7.8	[M − H]-	C8H8O	/
6	10.12	β-coumaric acid	163.0391	−5.7	[M − H]-	C9H8O3	119.0493[M-H-COO]-
7	11.35	Ferulic acid	193.0494	−6.6	[M − H]-	C10H10O4	134.0368[M-H–COO–CH3]-	D
8	12.32	5,7-Dihydrox-4′-methoxyisoflavone	329.0680	3.9	[M + HCOO]-	C16H12O5	/	A
9	14.27	Ferulic acid iso	193.0495	−6.0	[M − H]-	C10H10O4	178.0261 M-H- CH3]- 149.0598[M-H-COO]- 134.0368[M-H–COO–CH3]-	D
10	21.36	Ginsenoside Rg1a	845.4943	4.6	[M + HCOO]-	C42H72O14	799.4857[M − H]- 637.4313[M-H-Glc]-	B
11	21.71	Ginsenoside Re/ Notoginsenoside Re	991.5538	5.5	[M + HCOO]-	C48H82O18	945.5453[M − H]-	B
12	21.88	Dihydroactinidiolide	225.1117	−6.8	[M + HCOO]-	C11H16O2	/
13	23.36	(6aR,11aR)-3-hydroxy-9,10-dimethoxypterocar- pan-3-O-β-D-Glglucoside	507.1492	−3.1	[M + HCOO]-	C23H26O10	417.1175[M + HCOO–3CH3]- 273.0388 164.0463
14	24.41	Calycosina	283.0593	−6.4	[M − H]	C16H12O5	268.0356[M-H-CH3]-	A
15	29.66	4,7-dihydroxy-3-butylphthalide	221.0803	−7.6	[M − H]-	C12H14O4	177.0894[M-H-COO]-	B
16	32.05	Kinobeon A	355.1208	5.7	[M − H]-	C20H20O6	205.0851[M-H- C8H6O3]-	D
17	32.57	Senkyunolide F	205.0859	−5.6	[M − H]-	C12H14O3	161.0959[M-H-COO]-	B
18	34.54	Ginsenoside Rb1	1107.6018	5.6	[M + HCOO]-	C54H92O23	945.5424[M-H-Glc]- 783.4897[M-H-2Glc]- 621.4331[M-H-3Glc]-	B
19	34.56	Astragaloside Ⅴ/ Astragaloside Ⅵ/ AstragalosideⅦ	991.5530	4.7	[M + HCOO]-	C47H78O19	945.5424[M − H]- 783.4877[M-H-Glc]-	A
20	35.22	Formononetina	267.0655	−3.0	[M − H]-	C16H12O4	252.0411[M-H-CH3]- 223.0378[M + HCOO–C6H2O]- 195.0428[M + HCOO–C7H2O2]-	A
21	36.46	Ginsenoside Rb2/Ginsenoside Rb3/Ginsenoside Rc/ Vina-Ginsenoside R7/ Notoginsenoside L	1123.5929	2.1	[M + HCOO]-	C53H90O22	1077.5865[M − H]- 829.4590	B
22	37.16	Ginsenoside Rb2/ Ginsenoside Rb3/ Ginsenoside Rc/ Vina-Ginsenoside R7/ Notoginsenoside L	1123.5944	3.4	[M + HCOO]-	C53H90O22	1077.5865[M − H]-	B
23	38.37	Ginsenoside Rd/ Gypenoside XVII	991.5556	7.3	[M + HCOO]-	C48H82O18	945.5485[M − H]-	B
24	39.75	Cyclocephaloside II	871.4709	1.4	[M + HCOO]-	C43H70O15	530.3220 494.3231[M–HCOO–H-C15H23O8]-	A

^aIdentifcations confrmed with standard compound;/: Not detected.