Table 3.
EF SLP; Mitral valve closing speed (cm/s) [median (minimum-maximum)] after administration of metoclopramide and ondansetron in donkeys at different time points.
| Treatment | Time after administration (min) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| T0 | T15 | T30 | T60 | T90 | T120 | T180 | T240 | T300 | T360 | |
| Placebo | 6.9 (5.2–7.6) | 7 (5.2–7.5) | 6.9 (5.2–7.6)a | 6.4 (5.2–7.7)a | 6.8 (5.2–7.6)a | 6.9 (5.2–7.5)a | 6.9 (5.2–7.6)a | 6.9 (5.2–7.6)a | 6.9 (5.2–7.5) | 7 (5.2–7.6) |
| Metoclopramide 0.25 mg Kg−1 (n = 10) | 7 (5.2–7.5) | 6 (5.3–7.8) | 11.6 (7.3–15.8)*b | 9.3 (6.9–9.8)*b | 11.6 (7.6–12)*b | 12.3 (10–15.2)*b | 11.3 (7.5–15.3)*b | 10.9 (8.6–17.3)*b | 7.1 (7–7.3) | 7.2 (7–7.5) |
| Ondansetron 0.15 mg Kg−1 (n = 10) | 6.9 (5.2–7.2) | 6.8 (5.8–7.2) | 10.4 (8.6–11.9)*b | 10.2 (8.9–10.6)*ab | 11.5 (9.9–13.9)*b | 11.6 (10–12.7)*b | 11.6 (10–12.8)*b | 11.2 (10–12.9)*b | 7.1 (6–7.3) | 7 (6.2–8) |
a,b Variables with different superscript letters within the same time point significantly differ at p < 0.05.
Variables with (*) significantly differ at p < 0.05 over time.