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. 2023 Aug 23;10:1189710. doi: 10.3389/fvets.2023.1189710

Table 4.

DE SLP; Mitral valve opening speed (cm/s) [median (minimum-maximum)] after administration of metoclopramide and ondansetron in donkeys at different time points.

Treatment Time after administration (min)
T0 T15 T30 T60 T90 T120 T180 T240 T300 T360
Placebo 9.2 (5.3–11.6) 9.1 (5.3–11.6) 9.5 (5.3–11.6) 9.4 (5.3–11.6)a 9.5 (5.4–1.6) 9.1 (5.5–11.6)a 9.3 (5.3–11.6) 9.2 (5.3–11.6) 9.1 (5.3–11.6)a 9.5 (5.3–11.9)
Metoclopramide 0.25 mg Kg−1 (n = 10) 9.1 (5.3–11.6) 10 (8.1–13.9)* 11.6 (6.7–13.4)* 10 (9.3–13)*a 10.6 (9–3.1)* 11.2 (10–4.9)*b 11.1 (9.6–2.7)* 11.4 (4.8–12.2)* 12 (9.2–16.5)*b 9.2 (6.7–12.6)*
Ondansetron 0.15 mg Kg−1 (n = 10) 9.5 (5.3–11.6) 10.2 (8.7–13.4) 10.4 (7.2–11.5) 11.6 (10–2.8)ab 10 (9.3–11.4) 10.2 (7.6–11.9)a 11.5 (10.2–12) 10.6 (8.4–12.6) 10.9 (10–12.2)ab 10.6 (7.2–12.8)

a,b Variables with different superscript letters within the same time point significantly differ at p < 0.05.

Variables with (*) significantly differ at p < 0.05 over time.