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. 2023 Aug 23;17:1217368. doi: 10.3389/fncel.2023.1217368

TABLE 1.

Compound reference set including solvent used and reported mode(s) of action.

Compound Solvent Description Concentration (μM) References
Picrotoxin Ethanol GABAA receptor antagonist, used in research to induce seizures 1, 10, 100 Mackenzie et al., 2002
Gabazine Water SR95531 is GABAA receptor antagonist, used in research to induce seizures 0.1, 1, 10 Lindquist et al., 2005; Johnston, 2013
4-Aminopyridine DMSO Potassium channel blocker, used to induce seizures in in vivo experiments 10, 40, 100 Peña and Tapia, 2000
Pilocarpine hydrochloride Water Muscarinic acetylcholine (ACh) receptor agonist, used as in vivo model for epilepsy 10, 30, 100 Zimmerman, 1981; Marchi et al., 2007

GABA, gamma-aminobutyric acid.