Each graph uses output from mixed-effects modeling using age, sex, time of day (on a 24-hour clock), height, and weight. For these specific graphs, temperatures are for an average US person weighing 88.8 kg if male or 76.4 kg if female (A and C), aged 30 years (B and C), and with height 1.75 m if male or 1.62 m if female (A and B). To convert temperature to degrees Fahrenheit, multiply by 1.8 and add 32.