Fig. 7.

DUXAP10 promotes GC cell proliferation partly via regulating LATS1 and KLF2. a KLF2 and LATS1 protein levels were detected by western blot in BGC823 cells transfected with KLF2 or LATS1 vector. b MTT assays were used to determine the cell viability for LATS1 and KLF2 vector or empty vector transfected BGC823 and SGC7901 cells. c,d Edu staining and colony formation assays were used to determine the cell viability for LATS1, KLF2 vector or empty vector transfected cells. e,f MTT and colony formation assays showed that cell proliferation was partly rescued by KLF2 and LATS1 knockdown in DUXAP10 siRNA transfected cells. g The correlation between DUXAP10 and KLF2, or LATS1 expression was detected in 20 pairs of GC and corresponding noncancerous tissues by qRT-PCR