Table 2.
Patients characteristics, empirical antibiotic treatment and etiology for CAP in the study population
| Total (n = 1590) | |
|---|---|
| Male (%) | 831 (52%) |
| Mean age in years (SD) | 70.0 (15.7) |
| Comorbidities | |
| - Chronic obstructive pulmonary disease (COPD) (%) | 631 (40%) |
| - Congestive heart failure (%) | 165 (11%) |
| - Diabetes without complications (%) | 257 (16%) |
| - Diabetes with complications (%) | 81 (5%) |
| - Median Charlson comorbidity score (IQR) | 1 (0–2) |
| Treating hospital and city of location (%) | |
| - Hospital Sønderjylland | 208 (13%) |
| - Hospital South West Jutland | 157 (10%) |
| - Lillebaelt Hospital | 391 (25%) |
| - Odense University Hospital | 834 (52%) |
| Empirical antibiotic treatment < 24 h after admission | |
| - Piperacillin-tazobactam | 515 (32%) |
| - Beta-lactamase-sensitive penicillins monotherapy | 388 (24%) |
| - Combination therapy including macrolide | 166 (10%) |
| - Cephalosporin | 148 (9%) |
| - Fluoroquinolone monotherapy | 113 (7%) |
| - Amoxicillin/clavulanate | 96 (6%) |
| - Combination therapy including fluoroquinolone | 38 (2%) |
| - Macrolide monotherapy | 36 (2%) |
| - Amoxicillin or ampicillin | 33 (2%) |
| - Antibiotics targeting urinary tract infections | 13 (1%) |
| - Other | 44 (3%) |
| Etiology | |
| - Streptococcus pneumoniae | 396 (25%) |
| - Haemophilus influenzae | 381 (24%) |
| - Staphylococcus aureus | 315 (20%) |
| - Pseudomonas aeruginosa | 176 (11%) |
| - Moraxella catarrhalis | 128 (8%) |
| - Hemolytic streptococci | 81 (5%) |
| - LMC-pneumonia | 114 (7%) |
| - Mycoplasma pneumonia | 79 (5%) |
| - Legionella Pneumophila | 26 (2%) |
| - Chlamydophila Pneumoniae | 8 (1%) |
| CRB-65 score | (n = 872) |
| - CRB-65 = 0 | 29 (3%) |
| - CRB-65 = 1 | 212 (24%) |
| - CRB-65 = 2 | 481 (55%) |
| - CRB-65 = 3 | 149 (17%) |
| - CRB-65 = 4 | 1 (< 0%) |