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. 2023 Jul 25;24(9):e56230. doi: 10.15252/embr.202256230

Figure EV1. FBL is overexpressed in cancer cell lines and promotes cell proliferation.

Figure EV1

  • A, B
    Western blotting analyses of FBL expression in colon/lung cancer and normal cell lines.
  • C, D
    Cell lysates of monoclonal cell lines were immunoblotted with FBL antibodies to confirm the knockdown efficiency in HCT116/A549 cells.
  • E, F
    Cells were reconstituted with full‐length FBL and FBLE191A/D236A in HCT116/A549 cells. Protein expressions were examined by western blot with indicated antibodies.
  • G, H
    Cell viability assays were performed on control (siNC) and FBL knockdown (siFBL) NCM460/BEAS‐2B cells using CCK‐8 assays. The data are presented as mean ± SD from three independent experiments. The statistical significance was determined using Student's t‐test. ***P < 0.001.