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. 2023 Sep 5;13(9):e072167. doi: 10.1136/bmjopen-2023-072167

Table 4.

Adverse effects

Parameter Baseline
N=241
n (%)
Post-intervention
N=480
n (%)
Adjusted effect size (95% CI)*
Dosing errors 75 (31.1) 76 (15.8) 0.41 (0.28, 0.63)
Patients with any complications 15 (6.2) 17 (3.5) 0.59 (0.28, 1.22)
Acute kidney injury 5 (2.1) 1 (0.2)
New-onset allergy 3 (1.2) 6 (1.2)
Clostridioides difficile infection (hospital-associated) 0 (0.0) 1 (0.2)
Neutropenia 1 (0.4) 2 (0.4)
Allergy mismatch 1 (0.4) 3 (0.6)
Intolerance to medication 4 (1.7) 6 (1.2)

*Adjusted for sepsis without shock, Charlson score, MRSA infection risk, febrile neutropenia and palliation status.

MRSA, methicillin-resistant Staphylococcus aureus.