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. 2023 Aug 23;10:1201007. doi: 10.3389/fnut.2023.1201007

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Copyright © 2023 Janilkarn-Urena, Idrissova, Zhang, VanDreal, Sanghavi, Skinner, Cheng, Zhang, Watanabe, Asatryan, Cadenas and Davies.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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DHM increases production of anti-inflammatory cytokines compared to mice fed EtOH-only. Expression of (A) IL-1ra (*, **< 0.0001) is significantly reduced in mice receiving DHM compared to those fed EtOH-only. In addition, levels of circulating (B) IL-27 (*0.034) in the DHM-fed group are significantly higher than that in the No-EtOH group.