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. 2023 Aug 23;14:1240860. doi: 10.3389/fmicb.2023.1240860

Figure 3.

Figure 3

Phylogenetic analysis of DENV-1, based on a fragment of the E protein coding sequence. The phylogenetic tree was built using the maximum likelihood method with bootstrap of 1000 replicates. The five DENV-1 isolates generated in the study were aligned to 29 global reference sequences. All sequences retrieved from NCBI are identified in the format: accession number/ country/ year of isolation. Brazilian sequences: BR (Brazil), followed by the acronym of the Brazilian state. Regarding sequences generated in this study: four isolates (red dots, above) are closely related to other strains isolated in the Federal District (DF) and São Paulo (SP), in 2019. In addition, one isolate (red ball, below) is related to strains isolated in the state of Alagoas (AL), in 2019 and Amapá (AP), in 2015 (AP).