Table 1.
Baseline characteristics by relative slope tertile and diabetes
| Participant Characteristic | Million Veteran Program (n=109,570) | BioVU (n=7,300) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Participants with Diabetes (n=44,782) | Participants without Diabetes (n=64,788) | Participants with Diabetes (n=1,642) | Participants without Diabetes (n=5,658) | |||||||||
| Tertile of relative eGFR decline, %/yr | < −3.0 | −3.0 to 0.1 | >0.1 | < −1.4 | −1.4 to 0.5 | >0.5 | < −7.3 | (−7.3, +1.5) | >1.5 | < −3.9 | −3.9, 2.0 | >2.0 |
| N | 14,928 | 14,927 | 14,927 | 21,596 | 21,596 | 21,596 | 555 | 533 | 554 | 1,886 | 1,886 | 1,886 |
| Age, yr, mean (SD) | 67 (9) | 68 (8) | 67 (8) | 69 (10) | 69 (9) | 67 (10) | 65 (12) | 66 (11) | 66 (11) | 64 (17) | 63 (17) | 59 (22) |
| Female sex, n (%) | 477 (3) | 538 (4) | 716 (5) | 828 (4) | 1,184 (5) | 1,527 (7) | 271 (49) | 278 (52) | 259 (47) | 935 (50) | 1,025 (54) | 959 (51) |
| Non-Hispanic Black race, n (%) | 3,712 (25) | 2,273 (15) | 2,735 (18) | 3,404 (16) | 2,264 (10) | 3,055 (14) | 89 (16) | 68 (19) | 83 (15) | 254 (14) | 151 (8) | 231 (12) |
| eGFR, ml/min per 1.73 m2; mean (SD) | 51 (8) | 52 (7) | 52 (7) | 50 (8) | 53 (6) | 52 (7) | 48 (19) | 54 (16) | 46 (17) | 51 (19) | 56 (16) | 47 (17) |
| Follow-up time, yr; median (IQR) | 6 (4–10) | 8 (5–12) | 6 (4–10) | 9 (5–12) | 9 (5–12) | 7 (4–11) | 2 (1–6) | 5 (3–7) | 2 (1–4) | 2 (1–5) | 6 (4–9) | 2 (1–5) |
| Systolic BP, mm Hg; mean (SD) | 135 (19) | 131 (17) | 129 (17) | 134 (18) | 131 (16) | 129 (17) | 136 (23) | 134 (20) | 132 (22) | 133 (23) | 131 (46) | 129 (21) |
| Body mass index, kg/m2; mean (SD) | 32 (6) | 32 (6) | 33 (6) | 29 (5) | 29 (5) | 30 (5) | 32 (7) | 32 (7) | 33 (7) | 29 (7) | 28 (7) | 28 (7) |
| Microalbuminuria; n (%) | 3,917 (54) | 2,372 (31) | 2,067 (26) | 715 (36) | 334 (17) | 382 (18) | 130 (54) | 124 (35) | 86 (35) | 216 (41) | 142 (21) | 136 (28) |
IQR, interquartile range.