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Spline plot of hazard ratio for progressive CKD (solid curve) with 95% confidence interval (dashed curve) by distal tubular diameter. Wider superficial distal tubular diameter is a predictor of progressive CKD in both (A) unadjusted analyses and (B) analyses adjusted for superficial glomerular volume and clinical characteristics (age, sex, body mass index, hypertension, diabetes, postnephrectomy eGFR and proteinuria). Hazard ratios are relative to median distal tubular diameter.
