Table 1.
Baseline characteristics of 1367 patients with renal tumor
| Characteristic | Mean (SD) or N(%) or median (25%, 75%) |
|---|---|
| Clinical characteristics | |
| Age, yr | 63.9 (11.9) |
| Male | 876 (64.1%) |
| Race | |
| American Indian/Alaskan Native | 14 (1.0%) |
| Asian | 4 (0.3%) |
| Black | 22 (1.6%) |
| Native Hawaiian/Pacific Islander | 1 (0.1%) |
| White | 1269 (92.8%) |
| Unknown/Other | 57 (4.2%) |
| BMI, kg/m2 | 30.8 (6.7) |
| Hypertension | 921 (67.4%) |
| Diabetes mellitus | 186 (13.6%) |
| Kidney function | |
| Prenephrectomy eGFR, ml/min per 1.73 m2 | 72.1 (18.8) |
| Postnephrectomy eGFR, ml/min per 1.73 m2 | 51.2 (13.7) |
| 24-h urine protein, mga | 154 (87, 307) |
| Baseline biopsy measures | |
| Superficial glomerular volume, mm3 | 0.0025 (0.0011) |
| Middle glomerular volume, mm3 | 0.0032 (0.0012) |
| Deep glomerular volume, mm3 | 0.0029 (0.0011) |
| Superficial proximal tubular diameter, μm | 54.2 (6.4) |
| Middle proximal tubular diameter, μm | 58.1 (6.6) |
| Deep proximal tubular diameter, μm | 56.6 (6.5) |
| Superficial distal tubular diameter, μm | 43.1 (4.4) |
| Middle distal tubular diameter, μm | 46.9 (4.7) |
| Deep distal tubular diameter, μm | 47.2 (5.0) |
| % Luminal stenosis | 54.5 (15.5) |
| % Fibrosis | 3.6 (7.5) |
| IFTA foci density, per cm2 | 25.1 (20.8) |
| Macroscopic measuresb | |
| Cortex volume, cm3 | 125.0 (36.9) |
| Medulla volume, cm3 | 48.6 (15.4) |
| Tumor volumec, cm3 | 155 (61, 406) |
| Outcomes during follow-up | |
| Progressive CKD, % | 62 (4.5%) |
BMI, body mass index; IFTA, interstitial fibrosis and tubular atrophy.
a
Urine protein data missing in 183 patients.
b
Cortex and medulla volume could not be obtained in 704 patients because of poor cm differentiation on the images or lack of digital images.
c
Tumor volume missing in 172 patients because of lack of digital images.